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High cerebrospinal amyloid-β 42 is associated with normal cognition in individuals with brain amyloidosis

BACKGROUND: Brain amyloidosis does not invariably predict dementia. We hypothesized that high soluble 42-amino acid β amyloid (Aβ42) peptide levels are associated with normal cognition and hippocampal volume despite increasing brain amyloidosis. METHODS: This cross-sectional study of 598 amyloid-pos...

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Detalles Bibliográficos
Autores principales: Sturchio, Andrea, Dwivedi, Alok K., Young, Christina B., Malm, Tarja, Marsili, Luca, Sharma, Jennifer S., Mahajan, Abhimanyu, Hill, Emily J., Andaloussi, Samir EL, Poston, Kathleen L., Manfredsson, Fredric P., Schneider, Lon S., Ezzat, Kariem, Espay, Alberto J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413261/
https://www.ncbi.nlm.nih.gov/pubmed/34505023
http://dx.doi.org/10.1016/j.eclinm.2021.100988