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Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells

Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, has been shown to accelerate the progression of atherosclerosis (AS). However, the definite mechanisms remain elusive. Emerging evidence supports an association between mitochondrial dysfunction and AS. In our study, the impa...

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Detalles Bibliográficos
Autores principales: Xu, Tong, Dong, Qin, Luo, Yuxiao, Liu, Yanqing, Gao, Liang, Pan, Yaping, Zhang, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413291/
https://www.ncbi.nlm.nih.gov/pubmed/34475379
http://dx.doi.org/10.1038/s41368-021-00134-4