Japanese encephalitis virus live attenuated vaccine strains display altered immunogenicity, virulence and genetic diversity

Japanese encephalitis virus (JEV) is the etiological agent of Japanese encephalitis (JE). The most commonly used vaccine used to prevent JE is the live-attenuated strain SA14-14-2, which was generated by serial passage of the wild-type (WT) JEV strain SA14. Two other vaccine candidates, SA14-5-3 and...

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Detalles Bibliográficos
Autores principales: Davis, Emily H., Beck, Andrew S., Li, Li, White, Mellodee M., Greenberg, Marianne Banks, Thompson, Jill K., Widen, Steven G., Barrett, Alan D. T., Bourne, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413339/
https://www.ncbi.nlm.nih.gov/pubmed/34475404
http://dx.doi.org/10.1038/s41541-021-00371-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413339/
https://www.ncbi.nlm.nih.gov/pubmed/34475404
http://dx.doi.org/10.1038/s41541-021-00371-y

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