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Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity

Neuronatin (Nnat) has previously been reported to be part of a network of imprinted genes downstream of the chromatin regulator Trim28. Disruption of Trim28 or of members of this network, including neuronatin, results in an unusual phenotype of a bimodal body weight. To better characterise this vari...

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Detalles Bibliográficos
Autores principales: Cimino, Irene, Rimmington, Debra, Tung, Y. C. Loraine, Lawler, Katherine, Larraufie, Pierre, Kay, Richard G., Virtue, Samuel, Lam, Brian Y. H., Fagnocchi, Luca, Ma, Marcella K. L., Saudek, Vladimir, Zvetkova, Ilona, Vidal-Puig, Antonio, Yeo, Giles S. H., Farooqi, I. Sadaf, Pospisilik, J. Andrew, Gribble, Fiona M., Reimann, Frank, O’Rahilly, Stephen, Coll, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413370/
https://www.ncbi.nlm.nih.gov/pubmed/34475432
http://dx.doi.org/10.1038/s41598-021-96278-8