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Evaluation of connectivity map shows limited reproducibility in drug repositioning
The Connectivity Map (CMap) is a popular resource designed for data-driven drug repositioning using a large transcriptomic compendium. However, evaluations of its performance are limited. We used two iterations of CMap (CMap 1 and 2) to assess their comparability and reliability. We queried CMap 2 w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413422/ https://www.ncbi.nlm.nih.gov/pubmed/34475469 http://dx.doi.org/10.1038/s41598-021-97005-z |