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Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia risk

DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identi...

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Detalles Bibliográficos
Autores principales: Perzel Mandell, Kira A., Eagles, Nicholas J., Wilton, Richard, Price, Amanda J., Semick, Stephen A., Collado-Torres, Leonardo, Ulrich, William S., Tao, Ran, Han, Shizhong, Szalay, Alexander S., Hyde, Thomas M., Kleinman, Joel E., Weinberger, Daniel R., Jaffe, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413445/
https://www.ncbi.nlm.nih.gov/pubmed/34475392
http://dx.doi.org/10.1038/s41467-021-25517-3