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Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia risk
DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identi...
Autores principales: | Perzel Mandell, Kira A., Eagles, Nicholas J., Wilton, Richard, Price, Amanda J., Semick, Stephen A., Collado-Torres, Leonardo, Ulrich, William S., Tao, Ran, Han, Shizhong, Szalay, Alexander S., Hyde, Thomas M., Kleinman, Joel E., Weinberger, Daniel R., Jaffe, Andrew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413445/ https://www.ncbi.nlm.nih.gov/pubmed/34475392 http://dx.doi.org/10.1038/s41467-021-25517-3 |
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