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Unmethylated CpG motif-containing genomic DNA fragments of bacillus calmette-guerin improves immune response towards a DNA vaccine for COVID-19

The development of an effective vaccine to control the global coronavirus disease-2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus- 2 (SARS-CoV-2) is of utmost importance. In this study, a synthetic DNA-based vaccine candidate, known as pSV10-SARS-CoV-2, expressin...

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Detalles Bibliográficos
Autores principales: Zhou, Zehua, Zhang, Xinyu, Li, Qianqian, Fu, Lili, Wang, Meiyu, Liu, Shuo, Wu, Jiajing, Nie, Jianhui, Zhang, Li, Zhao, Chenyan, Jiang, Fei, An, Yimeng, Yu, Bin, Zheng, Haifa, Wang, Youchun, Zhao, Aihua, Huang, Weijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413458/
https://www.ncbi.nlm.nih.gov/pubmed/34521552
http://dx.doi.org/10.1016/j.vaccine.2021.08.103