Eukaryotic Box C/D methylation machinery has two non-symmetric protein assembly sites

Box C/D ribonucleoprotein complexes are RNA-guided methyltransferases that methylate the ribose 2’-OH of RNA. The central ‘guide RNA’ has box C and D motifs at its ends, which are crucial for activity. Archaeal guide RNAs have a second box C’/D’ motif pair that is also essential for function. This s...

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Detalles Bibliográficos
Autores principales: Höfler, Simone, Lukat, Peer, Blankenfeldt, Wulf, Carlomagno, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413462/
https://www.ncbi.nlm.nih.gov/pubmed/34475498
http://dx.doi.org/10.1038/s41598-021-97030-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413462/
https://www.ncbi.nlm.nih.gov/pubmed/34475498
http://dx.doi.org/10.1038/s41598-021-97030-y

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