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Comparison of promoter, DNA vector, and cationic carrier for efficient transfection of hMSCs from multiple donors and tissue sources

Human mesenchymal stem cells (hMSCs) are primary cells with high clinical relevance that could be enhanced through genetic modification. However, gene delivery, particularly through nonviral routes, is inefficient. To address the shortcomings of nonviral gene delivery to hMSCs, our lab has previousl...

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Detalles Bibliográficos
Autores principales: Kozisek, Tyler, Hamann, Andrew, Samuelson, Luke, Fudolig, Miguel, Pannier, Angela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413668/
https://www.ncbi.nlm.nih.gov/pubmed/34513295
http://dx.doi.org/10.1016/j.omtn.2021.06.018