Cargando…

Comparison of promoter, DNA vector, and cationic carrier for efficient transfection of hMSCs from multiple donors and tissue sources

Human mesenchymal stem cells (hMSCs) are primary cells with high clinical relevance that could be enhanced through genetic modification. However, gene delivery, particularly through nonviral routes, is inefficient. To address the shortcomings of nonviral gene delivery to hMSCs, our lab has previousl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kozisek, Tyler, Hamann, Andrew, Samuelson, Luke, Fudolig, Miguel, Pannier, Angela K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413668/ https://www.ncbi.nlm.nih.gov/pubmed/34513295 http://dx.doi.org/10.1016/j.omtn.2021.06.018

Ejemplares similares

Glucocorticoid Priming of Nonviral Gene Delivery to hMSCs Increases Transfection by Reducing Induced Stresses
por: Hamann, Andrew, et al.
Publicado: (2020)

IRX5 promotes adipogenesis of hMSCs by repressing glycolysis
por: Jiang, Bulin, et al.
Publicado: (2022)

Proliferation and Osteogenic Differentiation of hMSCs on Biomineralized Collagen
por: de Melo Pereira, Daniel, et al.
Publicado: (2020)

(18)F- based Quantification of the Osteogenic Potential of hMSCs
por: Grossner, Tobias, et al.
Publicado: (2020)

hMSCs possess the potential to differentiate into DP cells in vivo and in vitro
por: Wu, Minjuan, et al.
Publicado: (2012)

hMSCs as an alternative therapeutic option for asthma with neutrophil mediated inflammation
por: Cruz, Fernanda F., et al.
Publicado: (2018)

TMT-Based Quantitative Proteomics Analysis Reveals Differentially Expressed Proteins between Different Sources of hMSCs
por: Naudot, Marie, et al.
Publicado: (2023)

hMSCs suppress neutrophil-dominant airway inflammation in a murine model of asthma
por: Hong, Gyong Hwa, et al.
Publicado: (2017)

Low dose effect of bisphosphonates on hMSCs osteogenic response to titanium surface in vitro
por: Alqhtani, N.R., et al.
Publicado: (2017)

Decoupling the role of chemistry and microstructure in hMSCs response to an osteoinductive calcium phosphate ceramic
por: Galván-Chacón, V.P., et al.
Publicado: (2022)

hMSCs in contact with DMSO for cryopreservation: Experiments and modeling of osmotic injury and cytotoxic effect
por: Traversari, Gabriele, et al.
Publicado: (2022)

The osteogenic response of undifferentiated human mesenchymal stem cells (hMSCs) to mechanical strain is inversely related to body mass index of the donor
por: Friedl, Gerald, et al.
Publicado: (2009)

Xeno-Hybrid Bone Graft Releasing Biomimetic Proteins Promotes Osteogenic Differentiation of hMSCs
por: Zhu, Hao, et al.
Publicado: (2020)

Manipulation of miRNA activity accelerates osteogenic differentiation of hMSCs in engineered 3D scaffolds
por: Mariner, Peter D, et al.
Publicado: (2012)

Magnetic Nanoparticle Based Nonviral MicroRNA Delivery into Freshly Isolated CD105(+) hMSCs
por: Schade, Anna, et al.
Publicado: (2014)

Platelet lysate outperforms FCS and human serum for co-culture of primary human macrophages and hMSCs
por: Tylek, Tina, et al.
Publicado: (2019)

Transplantation of hMSCs Genome Edited with LEF1 Improves Cardio-Protective Effects in Myocardial Infarction
por: Cho, Hyun-Min, et al.
Publicado: (2020)

Impact of Tranexamic Acid on Chondrocytes and Osteogenically Differentiated Human Mesenchymal Stromal Cells (hMSCs) In Vitro
por: Wagenbrenner, Mike, et al.
Publicado: (2020)

Efficient Differentiation of Human Induced Pluripotent Stem Cell (hiPSC) Derived Hepatocyte-Like Cells on hMSCs Feeder
por: Mobarra, Naser, et al.
Publicado: (2014)

Comparative study on the effects of substrate stiffness on cell morphology and focal adhesion expression between hMSCs and AFSCs
por: Lowry, B, et al.
Publicado: (2012)

P2 Receptors Influence hMSCs Differentiation towards Endothelial Cell and Smooth Muscle Cell Lineages
por: Zhang, Yu, et al.
Publicado: (2020)

Precision 3D printed meniscus scaffolds to facilitate hMSCs proliferation and chondrogenic differentiation for tissue regeneration
por: Deng, Xingyu, et al.
Publicado: (2021)

MiR-33a Controls hMSCS Osteoblast Commitment Modulating the Yap/Taz Expression Through EGFR Signaling Regulation
por: Costa, Viviana, et al.
Publicado: (2019)

TSG-6 Produced by hMSCs Delays the Onset of Autoimmune Diabetes by Suppressing Th1 Development and Enhancing Tolerogenicity
por: Kota, Daniel J., et al.
Publicado: (2013)

Long Term Expansion of Bone Marrow-Derived hMSCs on Novel Synthetic Microcarriers in Xeno-Free, Defined Conditions
por: Hervy, Martial, et al.
Publicado: (2014)

Differentiation of Definitive Endoderm from Human Induced Pluripotent Stem Cells on hMSCs Feeder in a Defined Medium
por: Jaafarpour, Zahra, et al.
Publicado: (2016)

Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF‐1r Onto the Primary Cilium Associated With Cilia Elongation
por: Dalbay, Melis T., et al.
Publicado: (2015)

Evaluation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) on random and aligned polycaprolactone-polyaniline-gelatin scaffolds
por: KarbalaeiMahdi, Ali, et al.
Publicado: (2023)

The response of human macrophages to 3D printed titanium antibacterial implants does not affect the osteogenic differentiation of hMSCs
por: Garmendia Urdalleta, Amaia, et al.
Publicado: (2023)

High-throughput screening of clinically approved drugs that prime nonviral gene delivery to human Mesenchymal stem cells
por: Kozisek, Tyler, et al.
Publicado: (2020)

The increase of NADH fluorescence lifetime is associated with the metabolic change during osteogenic differentiation of human mesenchymal stem cells (hMSCs)
por: Guo, Han Wen, et al.
Publicado: (2012)

Verification of Long-Term Genetic Stability of hMSCs during Subculture after Internalization of Sunflower-Type Nanoparticles (SF-NPs)
por: Park, Ji Sun, et al.
Publicado: (2018)

Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth
por: Benavides, Oscar R., et al.
Publicado: (2023)

Preparation, characterization, and efficient transfection of cationic liposomes and nanomagnetic cationic liposomes
por: Samadikhah, Hamid Reza, et al.
Publicado: (2011)

Electro-magnetic field promotes osteogenic differentiation of BM-hMSCs through a selective action on Ca(2+)-related mechanisms
por: Petecchia, Loredana, et al.
Publicado: (2015)

Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-α Stimulated Gene/Protein 6
por: He, Zhigang, et al.
Publicado: (2016)

TUDCA-treated chronic kidney disease-derived hMSCs improve therapeutic efficacy in ischemic disease via PrP(C)
por: Yoon, Yeo Min, et al.
Publicado: (2019)

Characterisation of osteogenic and vascular responses of hMSCs to Ti-Co doped phosphate glass microspheres using a microfluidic perfusion platform
por: Peticone, Carlotta, et al.
Publicado: (2020)

Small RNA sequencing reveals a novel tsRNA‐06018 playing an important role during adipogenic differentiation of hMSCs
por: Wang, Tao, et al.
Publicado: (2020)

Effects of Different Basal Cell Culture Media upon the Osteogenic Response of hMSCs Evaluated by (99m)Tc-HDP Labeling
por: Grossner, Tobias, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_345qaj8g5b1dg2os065qb15quk