Cargando…

Exosome-mediated transfer of MIF confers temozolomide resistance by regulating TIMP3/PI3K/AKT axis in gliomas

Temozolomide (TMZ) resistance is an important cause of clinical treatment failure and poor prognosis in gliomas. Increasing evidence indicates that cancer-derived exosomes contribute to chemoresistance; however, the specific contribution of glioma-derived exosomes remains unclear. The aim of this st...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Q.T., Liu, B.Y., Ji, H.Y., Lan, Y.F., Tang, W.H., Zhou, J., Zhong, X.Y., Lian, C.L., Huang, Q.Z., Wang, C.Y., Xu, Y.M., Guo, H.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413833/
https://www.ncbi.nlm.nih.gov/pubmed/34514093
http://dx.doi.org/10.1016/j.omto.2021.08.004