Metformin preferentially enhances the radio-sensitivity of cancer stem-like cells with highly mitochondrial respiration ability in HMPOS

Metformin has many anti-cancer effects, alone or in combination with radiation. However, the mechanism underlying its radio-sensitized effect is still unclear, especially for cancer stem-like cells (CSCs). Here, the radio-sensitized effect of metformin was investigated, and its mechanism was reveale...

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Detalles Bibliográficos
Autores principales: Deguchi, Tatsuya, Hosoya, Kenji, Kim, Shango, Murase, Yusuke, Yamamoto, Kumiko, Bo, Tomoki, Yasui, Hironobu, Inanami, Osamu, Okumura, Mahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413836/
https://www.ncbi.nlm.nih.gov/pubmed/34514095
http://dx.doi.org/10.1016/j.omto.2021.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413836/
https://www.ncbi.nlm.nih.gov/pubmed/34514095
http://dx.doi.org/10.1016/j.omto.2021.08.007

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