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The aminoglycoside G418 hinders de novo prion infection in cultured cells

The study of prions and the discovery of candidate therapeutics for prion disease have been facilitated by the ability of prions to replicate in cultured cells. Paradigms in which prion proteins from different species are expressed in cells with low or no expression of endogenous prion protein (PrP)...

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Detalles Bibliográficos
Autores principales: Arshad, Hamza, Patel, Zeel, Mehrabian, Mohadeseh, Bourkas, Matthew E.C., Al-Azzawi, Zaid A.M., Schmitt-Ulms, Gerold, Watts, Joel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413896/
https://www.ncbi.nlm.nih.gov/pubmed/34390689
http://dx.doi.org/10.1016/j.jbc.2021.101073