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The aminoglycoside G418 hinders de novo prion infection in cultured cells
The study of prions and the discovery of candidate therapeutics for prion disease have been facilitated by the ability of prions to replicate in cultured cells. Paradigms in which prion proteins from different species are expressed in cells with low or no expression of endogenous prion protein (PrP)...
Autores principales: | Arshad, Hamza, Patel, Zeel, Mehrabian, Mohadeseh, Bourkas, Matthew E.C., Al-Azzawi, Zaid A.M., Schmitt-Ulms, Gerold, Watts, Joel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413896/ https://www.ncbi.nlm.nih.gov/pubmed/34390689 http://dx.doi.org/10.1016/j.jbc.2021.101073 |
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