A glutamate concentration‐biased allosteric modulator potentiates NMDA‐induced ion influx in neurons

Precisely controlled synaptic glutamate concentration is essential for the normal function of the N‐methyl D‐aspartate (NMDA) receptors. Atypical fluctuations in synaptic glutamate homeostasis lead to aberrant NMDA receptor activity that results in the pathogenesis of neurological and psychiatric di...

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Detalles Bibliográficos
Autores principales: Costa, Blaise M., Kwapisz, Lina Cortés, Mehrkens, Brittney, Bledsoe, Douglas N., Vacca, Bryanna N., Johnston, Tullia V., Razzaq, Rehan, Manickam, Dhanasekaran, Klein, Bradley G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413904/
https://www.ncbi.nlm.nih.gov/pubmed/34476911
http://dx.doi.org/10.1002/prp2.859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413904/
https://www.ncbi.nlm.nih.gov/pubmed/34476911
http://dx.doi.org/10.1002/prp2.859

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