Effectiveness of low-dose amitriptyline and mirtazapine for insomnia disorder: study protocol of a randomised, double-blind, placebo-controlled trial in general practice (the DREAMING study)

INTRODUCTION: For over more than a decade, low-dose amitriptyline and mirtazapine are prescribed off-label for insomnia. However, placebo-controlled evidence on these antidepressants for insomnia is still lacking. Therefore, the present trial aims to assess the effectiveness of low-dose amitriptylin...

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Detalles Bibliográficos
Autores principales: Bakker, Mette H, Hugtenburg, Jacqueline G, van Straten, Annemieke, van der Horst, Henriëtte E, Slottje, Pauline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
General practice / Family practice
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413934/
https://www.ncbi.nlm.nih.gov/pubmed/34475156
http://dx.doi.org/10.1136/bmjopen-2020-047142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8413934/
https://www.ncbi.nlm.nih.gov/pubmed/34475156
http://dx.doi.org/10.1136/bmjopen-2020-047142

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