Targeting HER2 in non-small-cell lung cancer (NSCLC): a glimpse of hope? An updated review on therapeutic strategies in NSCLC harbouring HER2 alterations

Non-small-cell lung cancer (NSCLC) harbouring HER2 alterations is now considered a distinct molecular subtype. The activation of HER2 in NSCLC occurs via three mechanisms, i.e. gene mutation (1%-4% of cases), gene amplification (2%-5%) and protein overexpression (2%-30%), with different prognostic a...

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Detalles Bibliográficos
Autores principales: Riudavets, M., Sullivan, I., Abdayem, P., Planchard, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414039/
https://www.ncbi.nlm.nih.gov/pubmed/34479034
http://dx.doi.org/10.1016/j.esmoop.2021.100260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414039/
https://www.ncbi.nlm.nih.gov/pubmed/34479034
http://dx.doi.org/10.1016/j.esmoop.2021.100260

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