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Citrullination of a phage-displayed human peptidome library reveals the fine specificities of rheumatoid arthritis-associated autoantibodies

BACKGROUND: Post-translational modifications (PTMs) on proteins can be targeted by antibodies associated with autoimmunity. Despite a growing appreciation for their intrinsic role in disease, there is a lack of highly multiplexed serological assays to characterize the fine specificities of PTM-direc...

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Detalles Bibliográficos
Autores principales: Román-Meléndez, Gabriel D., Monaco, Daniel R., Montagne, Janelle M., Quizon, Rachel S., Konig, Maximilian F., Astatke, Mekbib, Darrah, Erika, Larman, H. Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414044/
https://www.ncbi.nlm.nih.gov/pubmed/34481243
http://dx.doi.org/10.1016/j.ebiom.2021.103506