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Citrullination of a phage-displayed human peptidome library reveals the fine specificities of rheumatoid arthritis-associated autoantibodies
BACKGROUND: Post-translational modifications (PTMs) on proteins can be targeted by antibodies associated with autoimmunity. Despite a growing appreciation for their intrinsic role in disease, there is a lack of highly multiplexed serological assays to characterize the fine specificities of PTM-direc...
Autores principales: | Román-Meléndez, Gabriel D., Monaco, Daniel R., Montagne, Janelle M., Quizon, Rachel S., Konig, Maximilian F., Astatke, Mekbib, Darrah, Erika, Larman, H. Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414044/ https://www.ncbi.nlm.nih.gov/pubmed/34481243 http://dx.doi.org/10.1016/j.ebiom.2021.103506 |
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