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Estrogen exacerbates the nociceptive effects of peripheral serotonin on rat trigeminal sensory neurons

Orofacial pain disorders involving trigeminal sensory neurons disproportionately affect women and can be modulated by hormones, especially estrogen (E2). Proinflammatory mediators, like serotonin (5HT), can act on sensory neurons expressing the transient receptor potential vanilloid 1 (TRPV1) ion ch...

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Detalles Bibliográficos
Autores principales: Kaur, Sukhbir, McDonald, Hanna, Tongkhuya, Sirima, Lopez, Cierra M.C., Ananth, Sushmitha, Hickman, Taylor M., Averitt, Dayna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414175/
https://www.ncbi.nlm.nih.gov/pubmed/34504982
http://dx.doi.org/10.1016/j.ynpai.2021.100073