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MicroRNA-183 attenuates osteoarthritic pain by inhibiting the TGFα-mediated CCL2/CCR2 signalling axis

AIMS: MicroRNA-183 (miR-183) is known to play important roles in osteoarthritis (OA) pain. The aims of this study were to explore the specific functions of miR-183 in OA pain and to investigate the underlying mechanisms. METHODS: Clinical samples were collected from patients with OA, and a mouse mod...

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Detalles Bibliográficos
Autores principales: Tao, Zirong, Zhou, Yang, Zeng, Biyun, Yang, Xucheng, Su, Manman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414439/
https://www.ncbi.nlm.nih.gov/pubmed/34463129
http://dx.doi.org/10.1302/2046-3758.108.BJR-2019-0308.R2