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Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway

AIMS: Interleukin (IL)-1β is one of the major pathogenic regulators during the pathological development of intervertebral disc degeneration (IDD). However, effective treatment options for IDD are limited. Suramin is used to treat African sleeping sickness. This study aimed to investigate the pharmac...

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Detalles Bibliográficos
Autores principales: Liu, Zi-Miao, Lu, Cheng-Chang, Shen, Po-Chih, Chou, Shih-Hsiang, Shih, Chia-Lung, Chen, Jian-Chih, Tien, Yin Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Hip
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414441/
https://www.ncbi.nlm.nih.gov/pubmed/34372688
http://dx.doi.org/10.1302/2046-3758.108.BJR-2020-0041.R3