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Intra-articular low-dose parathyroid hormone (1-34) improves mobility and articular cartilage quality in a preclinical age-related knee osteoarthritis model

AIMS: Osteoarthritis (OA) is prevalent among the elderly and incurable. Intra-articular parathyroid hormone (PTH) ameliorated OA in papain-induced and anterior cruciate ligament transection-induced OA models; therefore, we hypothesized that PTH improved OA in a preclinical age-related OA model. METH...

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Detalles Bibliográficos
Autores principales: Chen, Chung-Hwan, Kang, Lin, Chang, Ling-Hua, Cheng, Tsung-Lin, Lin, Sung-Yen, Wu, Shun-Cheng, Lin, Yi-Shan, Chuang, Shu-Chun, Lee, Tien-Ching, Chang, Je-Ken, Ho, Mei-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414442/
https://www.ncbi.nlm.nih.gov/pubmed/34387115
http://dx.doi.org/10.1302/2046-3758.108.BJR-2020-0165.R2