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Priming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages

The nucleotide-binding domain, leucine-rich-repeat containing family, pyrin domain-containing 3 (NLRP3) inflammasome is essential in inflammation and inflammatory disorders. Phosphorylation at various sites on NLRP3 differentially regulates inflammasome activation. The Ser725 phosphorylation site on...

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Detalles Bibliográficos
Autores principales: Zhu, Kaixiang, Jin, Xuexiao, Chi, Zhexu, Chen, Sheng, Wu, Songquan, Sloan, Richard D., Lin, Xuai, Neculai, Dante, Wang, Di, Hu, Hu, Lu, Linrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414466/
https://www.ncbi.nlm.nih.gov/pubmed/34480147
http://dx.doi.org/10.1038/s41423-021-00761-1