Nickel-Catalyzed Enantioselective Synthesis of Pre-Differentiated Homoallylic syn- or anti-1,2-Diols from Aldehydes and Dienol Ethers

[Image: see text] Nickel catalysis allied with cyclodiphosphazane or VAPOL-derived phosphoramidite ligands provides selective access to monoprotected vicinal diols by reductive coupling of dienol ethers and aldehydes. The observed regioselectivity is unprecedented, in that the diene reacts at the le...

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Detalles Bibliográficos
Autores principales: Davies, Thomas Q., Murphy, John J., Dousset, Maxime, Fürstner, Alois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414482/
https://www.ncbi.nlm.nih.gov/pubmed/34410708
http://dx.doi.org/10.1021/jacs.1c07042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414482/
https://www.ncbi.nlm.nih.gov/pubmed/34410708
http://dx.doi.org/10.1021/jacs.1c07042

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