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Prominent Hyperproinsulinemia in a Middle Age Patient

INTRODUCTION: Insulin is synthesized in the β-cells from preproinsulin. Preproinsulin becomes proinsulin after leaving the signal peptide. Proinsulin is separated into C-peptide and insulin by 2 enzymes. Hyperproinsulinemia is suspected to be a pancreatic β-cell defect that is augmented by the incre...

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Detalles Bibliográficos
Autores principales: Yoshino, Hiroshi, Kawakami, Kyoko, Yoshino, Kei, Yoshino, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414601/
https://www.ncbi.nlm.nih.gov/pubmed/34483693
http://dx.doi.org/10.1177/11795476211042241