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Prominent Hyperproinsulinemia in a Middle Age Patient
INTRODUCTION: Insulin is synthesized in the β-cells from preproinsulin. Preproinsulin becomes proinsulin after leaving the signal peptide. Proinsulin is separated into C-peptide and insulin by 2 enzymes. Hyperproinsulinemia is suspected to be a pancreatic β-cell defect that is augmented by the incre...
Autores principales: | Yoshino, Hiroshi, Kawakami, Kyoko, Yoshino, Kei, Yoshino, Gen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414601/ https://www.ncbi.nlm.nih.gov/pubmed/34483693 http://dx.doi.org/10.1177/11795476211042241 |
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