Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply

The medium-chain fatty acids octanoic acid (C8) and decanoic acid (C10) are gaining attention as beneficial brain fuels in several neurological disorders. The protective effects of C8 and C10 have been proposed to be driven by hepatic production of ketone bodies. However, plasma ketone levels correl...

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Detalles Bibliográficos
Autores principales: Andersen, Jens V., Westi, Emil W., Jakobsen, Emil, Urruticoechea, Nerea, Borges, Karin, Aldana, Blanca I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414667/
https://www.ncbi.nlm.nih.gov/pubmed/34479615
http://dx.doi.org/10.1186/s13041-021-00842-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414667/
https://www.ncbi.nlm.nih.gov/pubmed/34479615
http://dx.doi.org/10.1186/s13041-021-00842-2

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