The antioxidant N-acetylcysteine promotes immune response and inhibits epithelial-mesenchymal transition to alleviate pulmonary fibrosis in chronic obstructive pulmonary disease by suppressing the VWF/p38 MAPK axis

BACKGROUND/AIM: N-Acetylcysteine (NAC) demonstrates applications in the prevention of exacerbation of chronic obstructive pulmonary disease (COPD). COPD is often characterized by fibrosis of the small airways. This study aims at investigating the physiological mechanisms by which NAC might mediate t...

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Detalles Bibliográficos
Autores principales: Zhu, Lanlan, Xu, Fei, Kang, Xiuhua, Zhou, Jing, Yao, Qinqin, Lin, Yang, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414683/
https://www.ncbi.nlm.nih.gov/pubmed/34479474
http://dx.doi.org/10.1186/s10020-021-00342-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414683/
https://www.ncbi.nlm.nih.gov/pubmed/34479474
http://dx.doi.org/10.1186/s10020-021-00342-y

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