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HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury
BACKGROUND: Endothelial cell (EC) injury accelerates the progression of diabetic macrovascular complications. Hypoxia is an important cause of EC injury. Hypoxia-inducible factor-1 alpha (HIF-1α) is an important hypoxia regulatory protein. Our previous studies showed that high-glucose and hypoxic co...
Autores principales: | Zhao, Min, Wang, Shaoting, Zuo, Anna, Zhang, Jiaxing, Wen, Weiheng, Jiang, Weiqiang, Chen, Hong, Liang, Donghui, Sun, Jia, Wang, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414688/ https://www.ncbi.nlm.nih.gov/pubmed/34479471 http://dx.doi.org/10.1186/s11658-021-00283-8 |
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