Combinational blockade of MET and PD-L1 improves pancreatic cancer immunotherapeutic efficacy

BACKGROUND: Dysregulated expression and activation of receptor tyrosine kinases (RTKs) are associated with a range of human cancers. However, current RTK-targeting strategies exert little effect on pancreatic cancer, a highly malignant tumor with complex immune microenvironment. Given that immunothe...

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Detalles Bibliográficos
Autores principales: Li, Enliang, Huang, Xing, Zhang, Gang, Liang, Tingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414725/
https://www.ncbi.nlm.nih.gov/pubmed/34479614
http://dx.doi.org/10.1186/s13046-021-02055-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414725/
https://www.ncbi.nlm.nih.gov/pubmed/34479614
http://dx.doi.org/10.1186/s13046-021-02055-w

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