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Investigating the effect of an identified mutation within a critical site of PAS domain of WalK protein in a vancomycin-intermediate resistant Staphylococcus aureus by computational approaches

BACKGROUND: Vancomycin-intermediate resistant Staphylococcus aureus (VISA) is becoming a common cause of nosocomial infections worldwide. VISA isolates are developed by unclear molecular mechanisms via mutations in several genes, including walKR. Although studies have verified some of these mutation...

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Detalles Bibliográficos
Autores principales: Baseri, Neda, Najar-Peerayeh, Shahin, Bakhshi, Bita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414773/
https://www.ncbi.nlm.nih.gov/pubmed/34474665
http://dx.doi.org/10.1186/s12866-021-02298-9