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Prostaglandin E(2) Dilates Intracerebral Arterioles When Applied to Capillaries: Implications for Small Vessel Diseases
Prostaglandin E(2) (PGE(2)) has been widely proposed to mediate neurovascular coupling by dilating brain parenchymal arterioles through activation of prostanoid EP4 receptors. However, our previous report that direct application of PGE(2) induces an EP1-mediated constriction strongly argues against...
Autores principales: | Rosehart, Amanda C., Longden, Thomas A., Weir, Nick, Fontaine, Jackson T., Joutel, Anne, Dabertrand, Fabrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414797/ https://www.ncbi.nlm.nih.gov/pubmed/34483880 http://dx.doi.org/10.3389/fnagi.2021.695965 |
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