Siponimod: Disentangling disability and relapses in secondary progressive multiple sclerosis

BACKGROUND: In multiple sclerosis, impact of treatment on disability progression can be confounded if treatment also reduces relapses. OBJECTIVE: To distinguish siponimod’s direct effects on disability progression from those on relapses in the EXPAND phase 3 trial. METHODS: Three estimands, one base...

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Detalles Bibliográficos
Autores principales: Cree, Bruce AC, Magnusson, Baldur, Rouyrre, Nicolas, Fox, Robert J, Giovannoni, Gavin, Vermersch, Patrick, Bar-Or, Amit, Gold, Ralf, Piani Meier, Daniela, Karlsson, Göril, Tomic, Davorka, Wolf, Christian, Dahlke, Frank, Kappos, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414818/
https://www.ncbi.nlm.nih.gov/pubmed/33205682
http://dx.doi.org/10.1177/1352458520971819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414818/
https://www.ncbi.nlm.nih.gov/pubmed/33205682
http://dx.doi.org/10.1177/1352458520971819

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