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High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients

BACKGROUND: Progressive multifocal leukoencephalopathy (PML) can in rare cases occur in natalizumab-treated patients with high serum anti-JCPyV antibodies, hypothetically due to excessive blockade of immune cell migration. OBJECTIVE: Immune cell recruitment to the central nervous system (CNS) was as...

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Detalles Bibliográficos
Autores principales: Schneider-Hohendorf, Tilman, Schulte-Mecklenbeck, Andreas, Ostkamp, Patrick, Janoschka, Claudia, Pawlitzki, Marc, Luessi, Felix, Zipp, Frauke, Meuth, Sven G, Klotz, Luisa, Wiendl, Heinz, Gross, Catharina C, Schwab, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414828/
https://www.ncbi.nlm.nih.gov/pubmed/33150829
http://dx.doi.org/10.1177/1352458520970103