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IntelliCage Automated Behavioral Phenotyping Reveals Behavior Deficits in the 3xTg-AD Mouse Model of Alzheimer’s Disease Associated With Brain Weight

Transgenic rodent models of Alzheimer’s disease (AD) were designed to study mechanisms of pathogenesis and connect these mechanisms with cognitive decline. Measurements of cognition in rodents can be confounded, however, by human handling and interaction; the IntelliCage was created to circumvent th...

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Detalles Bibliográficos
Autores principales: Winslow, Wendy, McDonough, Ian, Tallino, Savannah, Decker, Annika, Vural, Austin S., Velazquez, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414893/
https://www.ncbi.nlm.nih.gov/pubmed/34483889
http://dx.doi.org/10.3389/fnagi.2021.720214