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Activation of the Thiazide-Sensitive Sodium-Chloride Cotransporter by Beta3-Adrenoreceptor in the Distal Convoluted Tubule

We previously showed that the beta-3 adrenergic receptor (BAR3) is expressed in most segments of the nephron where its agonism promotes a potent antidiuretic effect. We localized BAR3 in distal convoluted tubule (DCT) cells expressing the thiazide-sensitive sodium-chloride cotransporter (NCC). Aim o...

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Detalles Bibliográficos
Autores principales: Milano, Serena, Carmosino, Monica, Gerbino, Andrea, Saponara, Ilenia, Lapi, Dominga, Dal Monte, Massimo, Bagnoli, Paola, Svelto, Maria, Procino, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414899/
https://www.ncbi.nlm.nih.gov/pubmed/34483955
http://dx.doi.org/10.3389/fphys.2021.695824