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The Pathogenesis of Eosinophilic Asthma: A Positive Feedback Mechanism That Promotes Th2 Immune Response via Filaggrin Deficiency

Eosinophilic asthma (EA) is a common subtype of asthma and often progresses to severe disease. In order to understand its pathogenesis, targeted next-generation gene sequencing was performed on 77 Chinese EA patients and 431 Chinese healthy controls to obtain differential genomic variations. Among t...

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Detalles Bibliográficos
Autores principales: Gao, Wei, Gong, Jiuyu, Mu, Mi, Zhu, Yujin, Wang, Wenjuan, Chen, Wen, Han, Guojing, Hu, Hong, Bao, Pengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8414997/
https://www.ncbi.nlm.nih.gov/pubmed/34484176
http://dx.doi.org/10.3389/fimmu.2021.672312