EVT‐701 is a novel selective and safe mitochondrial complex 1 inhibitor with potent anti‐tumor activity in models of solid cancers

Targeting the first protein complex of the mitochondrial electron transport chain (MC1) in cancer has become an attractive therapeutic approach in the recent years, given the metabolic vulnerabilities of cancer cells. The anticancer effect exerted by the pleiotropic drug metformin and the associated...

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Detalles Bibliográficos
Autores principales: Luna Yolba, Raquel, Visentin, Virgile, Hervé, Caroline, Chiche, Johanna, Ricci, Jean‐Ehrland, Méneyrol, Jérôme, Paillasse, Michaël R., Alet, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415080/
https://www.ncbi.nlm.nih.gov/pubmed/34478236
http://dx.doi.org/10.1002/prp2.854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415080/
https://www.ncbi.nlm.nih.gov/pubmed/34478236
http://dx.doi.org/10.1002/prp2.854

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