Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART(®) Molecules

Bispecific HIVxCD3 DART molecules that co-engage the viral envelope glycoprotein (Env) on HIV-1-infected cells and the CD3 receptor on CD3+ T cells are designed to mediate the cytolysis of HIV-1-infected, Env-expressing cells. Using a novel ex vivo system with cells from rhesus macaques (RMs) infect...

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Detalles Bibliográficos
Autores principales: Tuyishime, Marina, Dashti, Amir, Faircloth, Katelyn, Jha, Shalini, Nordstrom, Jeffrey L., Haynes, Barton F., Silvestri, Guido, Chahroudi, Ann, Margolis, David M., Ferrari, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415083/
https://www.ncbi.nlm.nih.gov/pubmed/34484212
http://dx.doi.org/10.3389/fimmu.2021.710273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415083/
https://www.ncbi.nlm.nih.gov/pubmed/34484212
http://dx.doi.org/10.3389/fimmu.2021.710273

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