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TNF-α–Induced miR-21-3p Promotes Intestinal Barrier Dysfunction by Inhibiting MTDH Expression

Intestinal barrier dysfunction is characterized by increased intestinal permeability to lumen endotoxin, showing remarkable predisposition to immune enteropathy, and colorectal cancer tumor necrosis factor (TNF)-α is associated with this pathological process, while the mechanism remains unknown. In...

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Detalles Bibliográficos
Autores principales: Jiang, Zhifeng, Yang, Feiyu, Qie, Jingbo, Jin, Chaoyuan, Zhang, Feng, Shen, Jie, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415152/
https://www.ncbi.nlm.nih.gov/pubmed/34483933
http://dx.doi.org/10.3389/fphar.2021.722283