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Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat

While current therapeutic strategies for people living with human immunodeficiency virus type 1 (HIV-1) suppress virus replication peripherally, viral proteins such as transactivator of transcription (Tat) enter the central nervous system early upon infection and contribute to chronic inflammatory c...

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Detalles Bibliográficos
Autores principales: League, Alexis F., Gorman, Benjamin L., Hermes, Douglas J., Johnson, Clare T., Jacobs, Ian R., Yadav-Samudrala, Barkha J., Poklis, Justin L., Niphakis, Micah J., Cravatt, Benjamin F., Lichtman, Aron H., Ignatowska-Jankowska, Bogna M., Fitting, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415271/
https://www.ncbi.nlm.nih.gov/pubmed/34484091
http://dx.doi.org/10.3389/fneur.2021.651272