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REST is a major negative regulator of endocrine differentiation during pancreas organogenesis

Multiple transcription factors have been shown to promote pancreatic β-cell differentiation, yet much less is known about negative regulators. Earlier epigenomic studies suggested that the transcriptional repressor REST could be a suppressor of endocrinogenesis in the embryonic pancreas. However, pa...

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Detalles Bibliográficos
Autores principales: Rovira, Meritxell, Atla, Goutham, Maestro, Miguel Angel, Grau, Vane, García-Hurtado, Javier, Maqueda, Maria, Mosquera, Jose Luis, Yamada, Yasuhiro, Kerr-Conte, Julie, Pattou, Francois, Ferrer, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415321/
https://www.ncbi.nlm.nih.gov/pubmed/34385258
http://dx.doi.org/10.1101/gad.348501.121