Hydroxyl radical mediated damage of proteins in low oxygen solution investigated using X-ray footprinting mass spectrometry

In the method of X-ray footprinting mass spectrometry (XFMS), proteins at micromolar concentration in solution are irradiated with a broadband X-ray source, and the resulting hydroxyl radical modifications are characterized using liquid chromatography mass spectrometry to determine sites of solvent...

Descripción completa

Detalles Bibliográficos
Autores principales: Kristensen, Line G., Holton, James M., Rad, Behzad, Chen, Yan, Petzold, Christopher J., Gupta, Sayan, Ralston, Corie Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Radiation Damage
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415330/
https://www.ncbi.nlm.nih.gov/pubmed/34475282
http://dx.doi.org/10.1107/S1600577521004744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415330/
https://www.ncbi.nlm.nih.gov/pubmed/34475282
http://dx.doi.org/10.1107/S1600577521004744

Ejemplares similares