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A SAXS-based approach to rationally evaluate radical scavengers – toward eliminating radiation damage in solution and crystallographic studies

X-ray-based techniques are a powerful tool in structural biology but the radiation-induced chemistry that results can be detrimental and may mask an accurate structural understanding. In the crystallographic case, cryocooling has been employed as a successful mitigation strategy but also has its lim...

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Detalles Bibliográficos
Autores principales: Stachowski, Timothy R., Snell, Mary E., Snell, Edward H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415334/
https://www.ncbi.nlm.nih.gov/pubmed/34475280
http://dx.doi.org/10.1107/S1600577521004045