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Parental methylome reprogramming in human uniparental blastocysts reveals germline memory transition

Uniparental embryos derived from only the mother (gynogenetic [GG]) or the father (androgenetic [AG]) are unique models for studying genomic imprinting and parental contributions to embryonic development. Human parthenogenetic embryos can be obtained following artificial activation of unfertilized o...

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Detalles Bibliográficos
Autores principales: Xu, Jiawei, Shu, Yimin, Yao, Guidong, Zhang, Yu, Niu, Wenbin, Zhang, Yile, Ma, Xueshan, Jin, Haixia, Zhang, Fuli, Shi, Senlin, Wang, Yang, Song, Wenyan, Dai, Shanjun, Cheng, Luyao, Zhang, Xiangyang, Xie, Wei, Hsueh, Aaron J., Sun, Yingpu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415376/
https://www.ncbi.nlm.nih.gov/pubmed/34330789
http://dx.doi.org/10.1101/gr.273318.120