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rGO/Silk Fibroin-Modified Nanofibrous Patches Prevent Ventricular Remodeling via Yap/Taz-TGFβ1/Smads Signaling After Myocardial Infarction in Rats

Objective: After acute myocardial infarction (AMI), the loss of cardiomyocytes and dysregulation of extracellular matrix homeostasis results in impaired cardiac function and eventually heart failure. Cardiac patches have emerged as a potential therapeutic strategy for AMI. In this study, we fabricat...

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Detalles Bibliográficos
Autores principales: Feng, Yanjing, Zhao, Guoxu, Xu, Min, Xing, Xin, Yang, Lijun, Ma, Yao, Qi, Mengyao, Zhang, Xiaohui, Gao, Dengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415403/
https://www.ncbi.nlm.nih.gov/pubmed/34485415
http://dx.doi.org/10.3389/fcvm.2021.718055