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Lower Oligomeric Form of Surfactant Protein D in Murine Acute Lung Injury Induces M1 Subtype Macrophages Through Calreticulin/p38 MAPK Signaling Pathway

Surfactant protein D (SP-D) plays an important role in innate and adaptive immune responses. In this study, we found that the expression of total and de-oligomerized SP-D was significantly elevated in mice with lipopolysaccharide (LPS)-induced acute lung injury (ALI). To investigate the role of the...

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Detalles Bibliográficos
Autores principales: Li, Dandan, Pan, Linyue, Zhang, Xiaoju, Jiang, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415422/
https://www.ncbi.nlm.nih.gov/pubmed/34484184
http://dx.doi.org/10.3389/fimmu.2021.687506