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H2AFZ: A Novel Prognostic Marker in Canine Melanoma and a Predictive Marker for Resistance to CDK4/6 Inhibitor Treatment

Uncontrolled proliferation is a key feature of tumor progression and malignancy. This suggests that cell-cycle related factors could be exploited as cancer biomarkers and that pathways specifically involved in the cell cycle, such as the Rb-E2F pathway, could be targeted as an effective anti-tumor t...

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Detalles Bibliográficos
Autores principales: Bongiovanni, Laura, Andriessen, Anneloes, Silvestri, Serenella, Porcellato, Ilaria, Brachelente, Chiara, de Bruin, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415453/
https://www.ncbi.nlm.nih.gov/pubmed/34485433
http://dx.doi.org/10.3389/fvets.2021.705359